Hezkue

£59.95

Hezkue ® is an oral spray presented in a mint-flavoured liquid format. It includes a metered pump that delivers a consistent amount with each press for easy, measured use.

Review Title

Oral spray format
Light mint flavour
Adjustable pump count
Simple shake–prime–spray steps

Hezkue Ready for innovation

Category: Erectile Dysfunction

AUC, area under curve
Data taken from a prospective open-label, single centre, two-way crossover study to evaluate the pharmacokinetics, safety and tolerability of 100 mg of HEZKUE^® and 100 mg Viagra^® tablets administered orally to 52 fasted healthy male volunteers.^3,4
* Data based on mean plasma concentration after application of 8 pumps of HEZKUE^® (100 mg sildenafil) vs. Viagra^® tablets (100 mg sildenafil). Initial absorption of HEZKUE^® (100 mg of sildenafil) was observed within 5 minutes after administration (0.615 ng/mL, p=0.012) vs.

Viagra^® 100 mg tablets, which showed no absorption at that time. The rate of absorption was not statistically significant overall (for all timepoints). The clinical significance of this has not been evaluated. HEZKUE^® should be taken approximately one hour before sexual activity.¹
** In a post hoc analysis, the AUC ratio for HEZKUE^® (100 mg sildenafil) was 3x higher than for Viagra^® tablets (100 mg sildenafil) 20 minutes after administration (646.92 vs. 199.21, p<0.01) by Minute 20. The clinical significance of this has not been evaluated.

Ready for efficacy and safety

AUC, area under curve; C_max, maximum plasma concentration T_max, time of the maximum plasma concentration

Data taken from a prospective open-label, single centre, two-way crossover study to evaluate the pharmacokinetics, safety and tolerability of 100 mg of HEZKUE^® and 100 mg Viagra^® tablets administered orally to 52 fasted healthy male volunteers.^3,4

*25 mg, 50 mg and 100 mg doses available in single oro-mucosal suspension spray.¹
**The clinical significance of this has not been evaluated.
^†In a post hoc analysis, the AUC ratio for HEZKUE^® (100 mg sildenafil) was 3x higher than for Viagra^®tablets (100 mg sildenafil) 20 minutes after administration (646.92 ng/mL/min vs. 199.21 ng/mL/min, p<0.01).

^††The absorption rate (C_max/T_max) of HEZKUE^® (100 mg sildenafil) was 2x that of Viagra^® tablets (100 mg sildenafil) (16.00 ng/mL/min vs. 7.84 ng/mL/min, p<0.01).
^‡The absorption rate (C_max/T_max) of HEZKUE^® (100 mg sildenafil) was statistically significantly faster than that of Viagra^® tablets (100 mg sildenafil) at times of 5–20 minutes. The rate of absorption was not statistically significantly faster overall (for all timepoints).

✔ The pump releases a set amount per press

✔ The spray is applied inside the mouth and swallowed

✔ Helps maintain consistent measuring

✔ Instructions guide each step

FAQ

What is Hezkue®?

Hezkue® is an oral spray presented in a mint-flavoured liquid format. It includes a metered pump that delivers a consistent amount with each press for easy, measured use.

How is Hezkue® used?

The spray is shaken, primed and then applied inside the mouth following the instructions provided on the label and inside the box. After spraying, the liquid is swallowed as part of the normal process of use.

What does the pump do?

The pump is designed to release a uniform amount every time it is pressed. This allows the user to follow the recommended number of sprays shown in the usage guide.

Can the number of sprays be adjusted?

Yes. The number of pumps can be adjusted according to the guidance included in the packaging. The instructions clearly outline how many sprays to use during each application.